NCAA Champions From District 6 Schools
Note: Since the NCAA Championships began in 1928, some schools have moved to other districts.
The wrestlers listed below wrestled for high schools that were in District 6 at the time that they were champions.
| Year | Wrestler | College | High School |
| 1929 | Joe Sapora | Illinois | Renovo |
| 1930 | Joe Sapora | Illinois | Renovo |
| 1935 | Howard Johnston | Penn State | State College |
| 1955 | Larry Fornicola | Penn State | Bellefonte |
| 1958 | Paul Powell | Pittsburgh | Lock Haven |
| 1959 | Ed Hamer | Lehigh | Philipsburg-Osceola |
| 1963 | Jim Nance | Syracuse | Indiana |
| 1965 | Jim Nance | Syracuse | Indiana |
| 1972 | Wade Schalles | Clarion | Hollidaysburg |
| 1973 | Wade Schalles | Clarion | Hollidaysburg |
| 1987 | Carlton Haselrig | Pitt-Johnstown | Greater Johnstown |
| 1988 | Rob Koll | North Carolina | State College |
| 1988 | Carlton Haselrig | Pitt-Johnstown | Greater Johnstown |
| 1989 | Carlton Haselrig | Pitt-Johnstown | Greater Johnstown |
| 2011 | Quentin Wright | Penn State | Bald Eagle Area |
| 2012 | Steve Bosak | Cornell | State College |
| 2013 | Quentin Wright | Penn State | Bald Eagle Area |